Our Publications

Original research related to cell-free nucleic acids (main authorship only):

1. Turchinovich, A., Weiz, L., Langheinz, A. & Burwinkel, B. Characterization of extracellular circulating microRNA. Nucleic Acids Res 39, 7223-7233 (2011).
2. Madhavan, D. et al. Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer. Clin Cancer Res 18, 5972-5982 (2012).
3. Turchinovich, A. & Burwinkel, B. Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma. RNA Biol 9, 1066-1075 (2012).
4. Cuk, K. et al. Circulating microRNAs in plasma as early detection markers for breast cancer. Int J Cancer 132, 1602-1612 (2013).
5. Cuk, K. et al. Plasma microRNA panel for minimally invasive detection of breast cancer. PLoS One 8, e76729 (2013).
6. Turchinovich, A., Weiz, L. & Burwinkel, B. Isolation of circulating microRNA associated with RNA-binding protein. Methods Mol Biol 1024, 97-107 (2013).
7. Turchinovich, A. et al. Capture and Amplification by Tailing and Switching (CATS). An ultrasensitive ligation-independent method for generation of DNA libraries for deep sequencing from picogram amounts of DNA and RNA. RNA Biol 11, 817-828 (2014).
8. Madhavan, D. et al. Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis. Breast Cancer Res Treat 146, 163-174 (2014).
9. Maierthaler, M. et al. Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer. Int J Cancer 140, 176-187 (2017).
10. Cheng, J. et al. Cell-free circulating DNA integrity is an independent predictor of impending breast cancer recurrence. Oncotarget 8, 54537-54547 (2017). 
11. Cheng, J. et al. Circulating free DNA integrity and concentration as independent prognostic markers in metastatic breast cancer. Breast Cancer Res Treat 169, 69-82 (2018). 

12. Nersisyan, S. et al. A Post-Processing Algorithm for miRNA Microarray Data. Int J Mol Sci 21 (2020).

13. Fischer, C. et al. Circulating miR-200 Family and CTCs in Metastatic Breast Cancer before, during, and after a New Line of Systemic Treatment. Int J Mol Sci 23 (2022).
14. Fischer, C. et al. Circulating miR-200 Family and CTCs in Metastatic Breast Cancer before, during, and after a New Line of Systemic Treatment. Int J Mol Sci 23 (2022).

Reviews:

1. Turchinovich, A., Weiz, L. & Burwinkel, B. Extracellular miRNAs: the mystery of their origin and function. Trends Biochem Sci 37, 460-465 (2012).

2. Turchinovich, A., Samatov, T. R., Tonevitsky, A. G. & Burwinkel, B. Circulating miRNAs: cell-cell communication function? Front Genet 4, 119 (2013).
   

3. Turchinovich, A. & Cho, W. C. The origin, function and diagnostic potential of extracellular microRNA in human body fluids. Front Genet 5, 30 (2014). 

4. Turchinovich, A., Tonevitsky, A. G., Cho, W. C. & Burwinkel, B. Check and mate to exosomal extracellular miRNA: new lesson from a new approach. Front Mol Bios 11, 2 (2015).
   

5. Turchinovich, A., Tonevitsky, A. G. & Burwinkel, B. Extracellular miRNA: A Collision of Two Paradigms. Trends Biochem Sci 41, 883-892 (2016).

6. Makarova J., Shkurnikov, M. U., Wicklein, D., Lange, T., Samatov, T. R., Turchinovich, A. A & Tonevitsky, A. G. Intracellular and extracellular microRNA: An update on localization and biological role. Progr Histochem and Cytochem 51, 33-49 (2015).

7. Turchinovich, A., Baranova, A., Drapkina, O. & Tonevitsky, A. Cell-Free Circulating Nucleic Acids as Early Biomarkers for NAFLD and NAFLD-Associated Disorders. Front Physiol 9, 1256 (2018).

8. Turchinovich, A., Drapkina, O. & Tonevitsky, A. Transcriptome of Extracellular Vesicles: State-of-the-Art. Front Immunol 10, 202 (2019).

9. Makarova, J., Turchinovich, A., Shkurnikov, M. & Tonevitsky, A. Extracellular miRNAs and Cell-Cell Communication: Problems and Prospects. Trends Biochem Sci 46, 640-651 (2021).